OZOILE®

Ozoile® enhances nature and defends it

What is Ozoile®

Ozoile®, Stable Ozonides with vitamin E acetate, is the active ingredient in all the Erbagil Medical Devices for the prevention and treatment of skin lesions. It is a biological inducer, obtained from a patented green technology process, in which Ozone binds to oleic acid forming Stable Ozonides in the products of their reaction, which Erbagil stabilized in its Research laboratories.

The effectiveness of Ozoile®

Ozoile® enhances nature and defends it thanks to the universal effectiveness of reductive oxide reactions. Thanks to the bioperoxides, in fact, the membranes of bacteria and fungi are oxidized and the microorganisms die. In higher organisms such as humans, on the other hand, cells attacked by bioperoxides in non-cytotoxic concentrations, enhance the immune system. Ozoile®, therefore, strengthens man's immune defenses, cures tissues from inflammation, regenerates them and protects them from microorganisms.

Ozoile®: how it was born

Ozoile®, Stable Ozonides with vitamin E acetate, is made in the laboratory. Firstly, pure oxygen or ambient air are conveyed into an ozonizing machine that transforms oxygen into a mixture of oxygen-ozone at different concentrations which, having bubbled into a reactor with the matrix to be ozonized, produces Stable Ozonides in the products of their reaction . The matrix to be ozonized is composed of organic extra virgin olive oil with an action enhanced by 300% compared to common oils, produced locally by the biological Cultivar of ORTOLANA DEL SANNIO. All the process that leads to the production of Ozoile® takes place under temperature and pressure control.

Ozoile®: how it acts

Ozoile® is an active ingredient and a biological inducer that regulates the main metabolic pathways, stimulates the endogenous defense system and through the regulation of gene transcription, promotes rapid tissue regeneration and repair of skin lesions. Ozoile® is also a powerful inducer that brings oxygen to tissues and acts as an anti-inflammatory and microbicide.

Microbicidal action of Ozoile®

Ozoile® is a powerful broad-spectrum microbicide due to its high affinity for the lipoprotein components of the bacterial and fungal wall and for the oxidizing action of bioperoxides. The following summary table shows the effectiveness of Ozoile®. In vitro tests conducted by the University of Pavia, demonstrate the ability of Ozoile® to inhibit the bacterial and fungal growth.

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Bacterial and fungal growth reduction (%) University of Pavia

Activation of tissue repair action of Ozoile®

In patients treated with Ozoile®, in red, the factors causing inflammation are reduced.

In patients treated with Ozoile®, in blue, the factors causing inflammation are reduced with better results than cortisone

In patients treated with Ozoile®, in blue, the factor that turns off inflammation increases

Re-epitelialization action of Ozoile®

Ozoile® adequately re-epithelizes the skin tissue because it increases the transcription of E-cadherins responsible for the correct adhesion between the neocellulas in formation.

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Azione di blocco della degenerazione tissutale di Ozoile®

Tissue degeneration caused by high levels of the TG2 enzyme responsible for cell death in chronic inflammatory processes stops in patients treated with Ozoile®

Tissue degeneration caused by high levels of the NOS2 enzyme responsible for cell death in chronic inflammatory processes stops in patients treated with Ozoile®

Activation action of the tissue repair of Ozoile®

In patients treated with Ozoile®, in blue, the HIF -1alfa factor is activated which induces the response to oxygen deficiency

In patients treated with Ozoile®, in blue, the VEGF factor is activated which promotes the formation of new blood vessels

Re-epithelialization action of Ozoile®

Ozoile® riepitelizza adeguatamente il tessuto cutaneo perché incrementa la trascrizione delle E-cadherine responsabili della corretta adesione fra le neocellule in formazione.

Ozoile® adequately re-epithelializes the skin tissue because it increases the transcription of the E-cadaterals responsible for the correct adhesion between the neocellules in formation.